Anti-SPSB2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA055225.25	25 µl		-		7 - 10 business days*		369.00€
ATA-HPA055225.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box... more

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Product information "Anti-SPSB2"

Protein function: Substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:15601820, PubMed:21199876). Negatively regulates nitric oxide (NO) production and limits cellular toxicity in activated macrophages by mediating the ubiquitination and proteasomal degradation of NOS2 (PubMed:21199876). Acts as a bridge which links NOS2 with the ECS E3 ubiquitin ligase complex components ELOC and CUL5 (PubMed:21199876). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 87% and to rat: 87%

Keywords:	Anti-SSB-2, Anti-SPSB2, Anti-GRCC9, Anti-Gene-rich cluster protein C9, Anti-SPRY domain-containing SOCS box protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA055225

Properties

Application:	IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MGQTALAGGS SSTPTPQALY PDLSCPEGLE ELLSAPPPDL GAQRRHGWNP KDCSENIEVK EGGLYFERR (ATA-APrEST83925)