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Track device being used
| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG44941.50 | 50 µg | - | - |
6 - 14 business days* |
559.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Required for the localization of dynein and dynactin to the mitotic kintochore.... more
Product information "Anti-Spindly / CCDC99"
Protein function: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067). Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494). Plays a role in cell migration (PubMed:30258100). [The UniProt Consortium]
| Keywords: | Anti-hSpindly, Anti-hSpindly, Anti-Protein Spindly, Anti-Protein Spindly, Anti-Arsenite-related gene 1 protein, Anti-Arsenite-related gene 1 protein, Anti-Rhabdomyosarcoma antigen MU-RMS-40.4A, Anti-Rhabdomyosarcoma antigen MU-RMS-40.4A, Anti-Coiled-coil |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG44941 |
Properties
| Application: | IHC (paraffin) |
| Antibody Type: | Monoclonal |
| Conjugate: | No |
| Host: | Mouse |
| Species reactivity: | human |
| Format: | Purified |
Database Information
| UniProt ID : | Q96EA4 | Matching products |
| Gene ID : | GeneID 54908 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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