Anti-SPG8/Strumpellin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A304-809A-T	10 µl (10 µg)		-		3 - 7 business days*		165.00€
A304-809A	100 µl (100 µg)		-		3 - 7 business days*		586.00€

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Protein function: Acts at least in part as component of the WASH core complex whose assembly at... more

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Product information "Anti-SPG8/Strumpellin"

Protein function: Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). May be involved in axonal outgrowth. Involved in cellular localization of ADRB2 (PubMed:23085491). Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7 (PubMed:23676666). [The UniProt Consortium]

Keywords:	Anti-KIAA0196, Anti-Strumpellin, Anti-WASH complex subunit 5, Anti-WASH complex subunit strumpellin
Supplier:	Bethyl Laboratories
Supplier-Nr:	A304-809A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: zebrafish, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A304-809A-T maps to a region between residue 1109 to 1159 of human WASH complex subunit strumpellin using the numbering given in entry Q12768.1 (GeneID 9897).
Format:	Antigen Affinity Purified