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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
042197.200 | 200 µl | - | - |
3 - 19 business days* |
728.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats... more
Product information "Anti-SPAK, ID (STK39, SPAK, STE20/SPS1-related proline-alanine-rich protein kinase, DCHT, Serine/thr"
SPAK is a serine/threonine kinase containing an N-terminal series of proline and alanine repeats (PAPA box), followed by a serine/threonine kinase catalytic domain, a nuclear localization signal, a consensus caspase cleavage recognition motif, and a C-terminal region. Northern blot analysis detects ubiquitous expression, most abundantly in brain and pancreas. SPAK can phosphorylate itself and an exogenous substrate in vitro. SPAK immunoprecipitates from transfected mammalian cells in a complex with another serine/threonine kinase that phosphorylates catalytically inactive SPAK. SPAK activates the p38 MAP kinase pathway in cotransfection assays. Full-length SPAK is expressed in the cytoplasm in transfected cells, while a mutant corresponding to caspase-cleaved STK39 localizes predominantly in the nucleus. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: | Anti-SPAK, Anti-DCHT, Anti-STK39, EC=2.7.11.1, Anti-Ste-20-related kinase, Anti-Serine/threonine-protein kinase 39, Anti-STE20/SPS1-related proline-alanine-rich protein kinase |
Supplier: | United States Biological |
Supplier-Nr: | 042197 |
Properties
Application: | ELISA, IHC, WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse |
Immunogen: | SPAK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 356~385 amino acids from the central region of human SPAK. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K08835 | Matching products |
UniProt ID : | Q9UEW8 | Matching products |
Gene ID | GeneID 27347 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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