Anti-SP100 (Nuclear Autoantigen Sp-100, Lysp100b, Nuclear Dot-associated Sp100 Protein, Speckled 100

SP100 forms a homodimer and may play a role in the control of gene expression. It localizes to nuclear bodies (NBs), also referred to as Kr-bodies, ND10, or PODs. Splice variants of SP100 heterodimerize. SP100 interacts with members of the HP1 family of nonhistone chromosomal protein, such as CBX5 and CBX3 via the PxVxL motif. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.