Anti-Sp1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-944A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-944A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-944A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Transcription factor that can activate or repress transcription in response to... more
Product information "Anti-Sp1"
Protein function: Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR- alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression. In complex with ATF7IP, maintains telomerase activity in cancer cells by inducing TERT and TERC gene expression. Isoform 3 is a stronger activator of transcription than isoform 1. Positively regulates the transcription of the core clock component ARNTL/BMAL1. [The UniProt Consortium]
Keywords: Anti-SP1, Anti-TSFP1, Anti-Transcription factor Sp1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-944A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Goat
Reactivity: Human, Mouse (Expected: X. Laevis, X. Tropicalis, Chicken, Goat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Naked Mole Rat, African Elephant, Crab-eating Macaque, Zebra Finch)
Immunogen: synthetic peptide. The epitope recognized by A303-944A-T maps to a region between residue 735 to 785 of human Sp1 Transcription Factor using the numbering given in entry NP_612482.2 (GeneID 6667).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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