Anti-SOX30

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA006159.25	25 µl		-		7 - 10 business days*		239.00€
ATA-HPA006159.100	100 µl		-		7 - 10 business days*		477.00€

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Protein function: Acts as both a transcriptional activator and repressor (PubMed:10359848,... more

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Product information "Anti-SOX30"

Protein function: Acts as both a transcriptional activator and repressor (PubMed:10359848, PubMed:29739711). Binds to the DNA sequence 5'-ACAAT- 3' and shows a preference for guanine residues surrounding this core motif (PubMed:10359848). Binds to its own promoter and activates its own transcription. Required to activate the expression of postmeiotic genes involved in spermiogenesis. Binds to the promoter region of CTNNB1 and represses its transcription which leads to inhibition of Wnt signaling (PubMed:29739711). Also inhibits Wnt signaling by binding to the CTNNB1 protein, preventing interaction of CTNNB1 with TCF7L2/TCF4 (PubMed:29739711). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 68% and to rat: 70%

Keywords:	Anti-SOX30, Anti-Transcription factor SOX-30
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA006159

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: SPSPVTLFQP SVSSAAQVAV QDPSLPVYPA LPPQRFTGPS QTDTHQLHSE ATHTVKQPTP VSLESANRIS SSASTAHARF ATSTIQPPRE YSSVSPCPRS APIPQASPIP HP (ATA-APrEST70845)