Anti-SOX2, clone SOX2/1791

Anti-SOX2, clone SOX2/1791
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3386SAF-100UG 100 µg - -

3 - 10 business days

1 mg/ml in 1X PBS, BSA free, sodium azide free. SOX2 is a member of the SRY-related HMG-box (SOX)... more
Product information "Anti-SOX2, clone SOX2/1791"
1 mg/ml in 1X PBS, BSA free, sodium azide free. SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. At present, 30 Sox genes have been identified. SOX2 is required for stem cell maintenance in the central nervous system, and it also regulates gene expression in the stomach. SOX2 is necessary for regulating multiple transcription factors that affect Oct 3/4 expression. An essential function of SOX2 is to stabilize embryonic stem cells in a pluripotent state by maintaining the requisite level of Oct 3/4 expression. Protein function: Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation. [The UniProt Consortium]
Keywords: Anti-SOX2, Anti-Transcription factor SOX-2, SOX2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3386SAF-100UG


Application: ELISA, WB, IHC (paraffin)
Antibody Type: Monoclonal
Clone: SOX2/1791
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: Amino acids 176-305 of the human protein were used as the immunogen for the SOX-2 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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