Anti-SOX12

Anti-SOX12
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA055052.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA055052.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3'.... more
Product information "Anti-SOX12"
Protein function: Transcription factor that binds to DNA at the consensus sequence 5'-ACCAAAG-3'. Acts as a transcriptional activator. Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation. Involved in the differentiation of naive CD4-positive T-cells into peripherally induced regulatory T (pT reg) cells under inflammatory conditions. Binds to the promoter region of the FOXP3 gene and promotes its transcription, and might thereby contribute to pT reg cell differentiation in the spleen and lymph nodes during inflammation. Plays a redundant role with SOX4 and SOX11 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 96%
Keywords: Anti-SOX12, Anti-SOX22, Anti-Protein SOX-22, Anti-Transcription factor SOX-12
Supplier: Atlas Antibodies
Supplier-Nr: HPA055052

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LDCSALDRDP DLQPPSGTSH FEFPD (ATA-APrEST91611)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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