Anti-Snail homolog 1 / SNAI1, N-terminal

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG64061.100	100 µg		-	-	6 - 14 business days*		784.00€

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Protein function: Involved in induction of the epithelial to mesenchymal transition (EMT),... more

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Product information "Anti-Snail homolog 1 / SNAI1, N-terminal"

Protein function: Involved in induction of the epithelial to mesenchymal transition (EMT), formation and maintenance of embryonic mesoderm, growth arrest, survival and cell migration. Binds to 3 E-boxes of the E-cadherin/CDH1 gene promoter and to the promoters of CLDN7 and KRT8 and, in association with histone demethylase KDM1A which it recruits to the promoters, causes a decrease in dimethylated H3K4 levels and represses transcription. Associates with EGR1 and SP1 to mediate tetradecanoyl phorbol acetate (TPA)-induced up- regulation of CDKN2B, possibly by binding to the CDKN2B promoter region 5'-TCACA-3. In addition, may also activate the CDKN2B promoter by itself. [The UniProt Consortium]

Keywords:	Anti-SNAH, Anti-SNAI1, Anti-Protein sna, Anti-Protein snail homolog 1, Anti-Zinc finger protein SNAI1
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG64061

Properties

Application:	ELISA, WB, IHC (paraffin)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human, mouse (Expected: rat)
Immunogen:	RKPSDPNRKPNY-C
Format:	Ammonium Sulfate Precipitated