Anti-SMYD2

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA029023.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA029023.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Protein-lysine N-methyltransferase that methylates both histones and... more

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Product information "Anti-SMYD2"

Protein function: Protein-lysine N-methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1. Specifically trimethylates histone H3 'Lys-4' (H3K4me3) in vivo. The activity requires interaction with HSP90alpha. Shows even higher methyltransferase activity on p53/TP53. Monomethylates 'Lys-370' of p53/TP53, leading to decreased DNA-binding activity and subsequent transcriptional regulation activity of p53/TP53. Monomethylates RB1 at 'Lys-860'. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 94% and to rat: 95%

Keywords:	Anti-SMYD2, Anti-KMT3C, Anti-HSKM-B, Anti-Lysine N-methyltransferase 3C, Anti-Histone methyltransferase SMYD2, Anti-N-lysine methyltransferase SMYD2, Anti-SET and MYND domain-containing protein 2
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA029023

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: KLLAVKEFES HLDKLDNEKK DLIQSDIAAL HHFYSKHLEF PDNDSLVVLF AQVNCNGFTI EDEELSHLGS AIFPDVALMN HSCCPNVIVT YKGTLAEVRA VQEIKP (ATA-APrEST76868)