Anti-SMG6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA042932.25	25 µl		-		7 - 10 business days*		246.00€
ATA-HPA042932.100	100 µl		-		7 - 10 business days*		491.00€

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Protein function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential... more

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Product information "Anti-SMG6"

Protein function: Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini (PubMed:19179534). May have a general role in telomere regulation (PubMed:12676087, PubMed:12699629). Promotes in vitro the ability of TERT to elongate telomeres (PubMed:12676087, PubMed:12699629). Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization (PubMed:12676087, PubMed:12699629). Binds to the single-stranded 5'-(GTGTGG)(4)GTGT-3' telomeric DNA, but not to a telomerase RNA template component (TER) (PubMed:12676087, PubMed:12699629). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 84% and to rat: 85%

Keywords:	Anti-SMG6, Anti-C17orf31, Anti-hSmg5/7a, EC=3.1.-.-, Anti-Smg-6 homolog, Anti-EST1-like protein A, Anti-Telomerase subunit EST1A, Anti-Ever shorter telomeres 1A, Anti-Telomerase-binding protein EST1A
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA042932

Properties

Application:	ICC, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: MAEGLERVRI SASELRGILA TLAPQAGSRE NMKELKEARP RKDNRRPDLE IYKPGLSRLR NKPKIKEPPG SEEFKDEIVN DRDCSAVENG TQPVKDVCKE LNNQEQNGPI DP (ATA-APrEST73945)