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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| 200-401-I16 | 100 µg | - | - |
6 - 10 business days* |
819.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-SMAD7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to... more
Product information "Anti-SMAD7"
Anti-SMAD7 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD7 from human, rat, sheep and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-SMAD7 from other sources has not been determined. Protein function: Antagonist of signaling by TGF-beta (transforming growth factor) type 1 receptor superfamily members, has been shown to inhibit TGF-beta (Transforming growth factor) and activin signaling by associating with their receptors thus preventing SMAD2 access. Functions as an adapter to recruit SMURF2 to the TGF-beta receptor complex. Also acts by recruiting the PPP1R15A- PP1 complex to TGFBR1, which promotes its dephosphorylation. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3 protein YWHAQ which acts as a negative regulator. [The UniProt Consortium]
| Keywords: | Anti-Smad7, Anti-SMAD7, Anti-MADH7, Anti-hSMAD7, Anti-SMAD 7, Anti-MAD homolog 7, Anti-MAD homolog 8, Anti-SMAD family member 7, Anti-Mothers against DPP homolog 8, Anti-Mothers against DPP homolog 7, Anti-Mothers against decapentaplegic homolog 8 |
| Supplier: | Rockland Immunochemicals |
| Supplier-Nr: | 200-401-I16 |
Properties
| Application: | WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse, rat |
| Immunogen: | SMAD7 peptide. |
| Format: | Purified |
Database Information
| KEGG ID : | K19631 | Matching products |
| UniProt ID : | O15105 | Matching products |
| Gene ID : | GeneID 4092 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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