Anti-SMAD6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55591.100	100 µl		-	-	10 - 15 business days*		616.00€

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Protein function: Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses... more

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Product information "Anti-SMAD6"

Protein function: Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [The UniProt Consortium]

Keywords:	Anti-SMAD6, Anti-Smad6, Anti-MADH6, Anti-hSMAD6, Anti-SMAD 6, Anti-MAD homolog 6, Anti-SMAD family member 6, Anti-Mothers against DPP homolog 6, Anti-Mothers against decapentaplegic homolog 6
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55591

Properties

Application:	WB, FC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse)
Immunogen:	KLH-conjugated synthetic peptide around aa. 358-386 (Center) of Human SMAD6
Format:	Purified