Anti-SMAD6

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
200-401-I15	100 µg		-	-	3 - 8 business days*		860.00€

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Anti-SMAD6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to... more

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Product information "Anti-SMAD6"

Anti-SMAD6 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-SMAD6 from Human, Mouse, New World monkey, Rat and Sheep based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-SMAD6 from other sources has not been determined. Protein function: Acts as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions. [The UniProt Consortium]

Keywords:	Anti-SMAD6, Anti-MADH6, Anti-Smad6, Anti-hSMAD6, Anti-SMAD 6, Anti-MAD homolog 6, Anti-SMAD family member 6, Anti-Mothers against DPP homolog 6, Anti-Mothers against decapentaplegic homolog 6
Supplier:	Rockland Immunochemicals
Supplier-Nr:	200-401-I15

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	peptide corresponding to two internal amino acid sequences in the human SMAD6 protein.
Format:	Purified