Anti-SLC25A23 / Mitochondrial ATP-Mg/Pi carrier protein 2

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Predicted to enable ATP transmembrane transporter activity. Involved in calcium import into the mitochondrion, positive regulation of mitochondrial calcium ion concentration, and regulation of cellular hyperosmotic salinity response. Located in mitochondrion. Protein function: Electroneutral antiporter that mediates the transport of adenine nucleotides through the inner mitochondrial membrane. Originally identified as an ATP-magnesium/inorganic phosphate antiporter, it also acts as a broad specificity adenyl nucleotide antiporter. By regulating the mitochondrial matrix adenine nucleotide pool could adapt to changing cellular energetic demands and indirectly regulate adenine nucleotide-dependent metabolic pathways (PubMed:15123600). Also acts as a regulator of mitochondrial calcium uptake and can probably transport trace amounts of other divalent metal cations in complex with ATP (PubMed:24430870, PubMed:28695448). In vitro, a low activity is also observed with guanyl and pyrimidine nucleotides (PubMed:15123600). [The UniProt Consortium]