Anti-SLC1A5 (Neutral Amino Acid Transporter B(0), ATB(0), Baboon M7 Virus Receptor, RD114/Simian Typ

Solute Carrier Family 1 Member 5 (Slc1a5/ASCT2) belongs to a family of sodium dependent amino acid transporters. Slc1a5 has a preference for transporting zwitter ions. Slc1a5 also functions as a cell surface receptor for endogenously inherited retroviruses of cats, baboons and humans as well as for horizontally transmitted type-D simian retroviruses. In addition, it has been associated with increased metabolism in malignant tumors. In prostate carcinoma ASCT2 positivity is correlated with more aggressive biological behavior. Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 15-20ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.