Anti-SLC12A1 (NKCC2, Kidney-specific Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chlo

Anti-SLC12A1 (NKCC2, Kidney-specific Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chlo
Item number Size Datasheet Manual SDS Delivery time Quantity Price
145168.100 100 µg - -

1 - 19 business days

480.00€
 
Solute carrier family 12 (sodium/potassium/chloride transporters), member 1, also called NKCC2 is... more
Product information "Anti-SLC12A1 (NKCC2, Kidney-specific Na-K-Cl symporter, Bumetanide-sensitive sodium-(potassium)-chlo"
Solute carrier family 12 (sodium/potassium/chloride transporters), member 1, also called NKCC2 is specifically found in cells of the thick ascending limb of the loop of Henle in nephrons, the basic functional units of the kidney. This gene is mapped to 15q21.1. This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. This gene plays a vital role in the regulation of ionic balance and cell volume. UniProt Number: Q13621, Gene ID: SLC12A1, Applications: Suitable for use in Western Blot, Immunohistochemistry (Paraffin and Frozen). Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Handling: Store at -20?C for one year. After reconstitution, store at 4?C for one month. Can also be aliquoted and stored frozen at -20?C for long term., Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 145168

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Format: Affinity Purified

Database Information

UniProt ID : Q13621 | Find alternatives

Handling & Safety

Storage: vT
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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