Anti-SIL

Anti-SIL
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A302-442A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A302-442A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A302-442A 100 µl (20 µg) -

3 - 9 business days*

465.00€
 
Protein function: Immediate-early gene. Plays an important role in embryonic development as well... more
Product information "Anti-SIL"
Protein function: Immediate-early gene. Plays an important role in embryonic development as well as in cellular growth and proliferation, its long-term silencing affects cell survival and cell cycle distribution as well as decreases CDK1 activity correlated with reduced phosphorylation of CDK1. Plays a role as a positive regulator of the sonic hedgehog pathway, acting downstream of PTCH1 (PubMed:16024801, PubMed:9372240). Plays an important role in the regulation of centriole duplication. Required for the onset of procentriole formation and proper mitotic progression. During procentriole formation, is essential for the correct loading of SASS6 and CENPJ to the base of the procentriole to initiate procentriole assembly (PubMed:22020124). [The UniProt Consortium]
Keywords: Anti-SIL, Anti-STIL, Anti-SCL-interrupting locus protein, Anti-TAL-1-interrupting locus protein
Supplier: Bethyl Laboratories
Supplier-Nr: A302-442A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Bovine, Horse, Rabbit, Guinea Pig_10141, Pig, Panda, Orangutan, Gorilla, Chimpanzee, African Elephant, Naked Mole Rat, Gray Short-tailed Opossum, Thirteen-lined Ground Squirrel, Little Brown Bat)
Immunogen: synthetic peptide. The epitope recognized by A302-442A-T maps to a region between residue 1237 and 1287 of human SCL/TAL1 interrupting locus using the numbering given in entry NP_003026.2 (GeneID 6491).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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