Anti-SIKE1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES10323.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES10323.100	100 µl		-	-	10 - 14 business days*		290.00€

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SIKE interacts with IKK-epsilon (IKBKE, MIM 605048) and TBK1 (MIM 604834) and acts as a... more

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Product information "Anti-SIKE1"

SIKE interacts with IKK-epsilon (IKBKE, MIM 605048) and TBK1 (MIM 604834) and acts as a suppressor of TLR3 (MIM 603029) and virus-triggered interferon activation pathways (Huang et al., 2005 [PubMed 16281057]).[supplied by OMIM, Mar 2008], Protein function: Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3. Inhibits TLR3- mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and RIGI. Does not inhibit NF- kappa-B activation pathways. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: Cytoplasm .

Keywords:	Anti-SIKE, Anti-SIKE1, Anti-Suppressor of IKBKE 1, Anti-Suppressor of IKK-epsilon, SIKE1 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES10323

Properties

Application:	WB, ELISA
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, rat, mouse
Immunogen:	Synthesized peptide derived from part region of human protein
MW:	22 kD
Format:	Purified