Anti-SIGLEC8, clone 7C9

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG11042.100	100 µg		-	-	6 - 14 business days*		641.00€

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Protein function: Putative adhesion molecule that mediates sialic-acid dependent binding to red... more

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Product information "Anti-SIGLEC8, clone 7C9"

Protein function: Putative adhesion molecule that mediates sialic-acid dependent binding to red blood cells (PubMed:10856141, PubMed:10625619). Preferentially binds to alpha-2,3-linked sialic acid. Also binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface (PubMed:10625619). Recognizes simultaneously epitopes having a terminal N-acetylneuraminic acid (sialic acid) and an underlying 6-O-sulfated galactose. Preferentially binds to Gal-6-sulfated sialyl-Lewis X glycan epitopes (PubMed:27357658). [The UniProt Consortium]

Keywords:	Anti-SAF2, Anti-SAF-2, Anti-SIGLEC8, Anti-Siglec-8, Anti-Sialoadhesin family member 2, Anti-Sialic acid-binding Ig-like lectin 8
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG11042

Properties

Application:	ELISA, FC, IP
Antibody Type:	Monoclonal
Clone:	7C9
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	SIGLEC8-Fc protein, containing entire extracellular region of Human Siglec-8 fused with the Fc region of Human IgG1
Format:	Affinity Purified