Anti-Shwachman-Bodian-Diamond Syndrome/SBDS

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A305-018A-T	10 µl (10 µg)		-		2 - 8 business days*		178.00€
A305-018A	100 µl (100 µg)		-		2 - 8 business days*		630.00€

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Protein function: Required for the assembly of mature ribosomes and ribosome biogenesis. Together... more

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Product information "Anti-Shwachman-Bodian-Diamond Syndrome/SBDS"

Protein function: Required for the assembly of mature ribosomes and ribosome biogenesis. Together with EFL1, triggers the GTP- dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Required for normal levels of protein synthesis. May play a role in cellular stress resistance. May play a role in cellular response to DNA damage. May play a role in cell proliferation. [The UniProt Consortium]

Keywords:	Anti-SBDS, Anti-CGI-97, Anti-Ribosome maturation protein SBDS, Anti-Shwachman-Bodian-Diamond syndrome protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A305-018A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: bovine, orangutan)
Immunogen:	synthetic peptide. The epitope recognized by A305-018A-T maps to a region between residue 175 to 225 of human Ribosome maturation protein SBDS using the numbering given in entry Q9Y3A5.4 (GeneID 51119).
Format:	Antigen Affinity Purified