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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
S1010-88B4.100 | 100 µg | - | - |
3 - 19 business days* |
978.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DEC-2 is a 54-56kD Class B member of the bHLH superfamily of proteins. It utilizes both DNA... more
Product information "Anti-SHARP1 (Class E Basic Helix-loop-helix Protein 41, bHLHe41, Class B Basic Helix-loop-helix Prot"
DEC-2 is a 54-56kD Class B member of the bHLH superfamily of proteins. It utilizes both DNA binding and protein-protein interaction to mediate E-box transcriptional repression. Physiologically, DEC-2 is proposed to be a regulator of the sleep cycle, particularly during periods of sleep deprivation. It also interacts with HIF-1 alpha neutralizing its activation of the VEGF gene during hypoxia. Human DEC-2 is 482aa in length. It contains a DNA binding motif aa45-57, an HLH region aa58-100, an Orange domain that may impart specificity to protein-protein interactions aa131-166 and a Gly/Ala-rich region aa297-431. DEC-2 forms homodimers, and heterodimers with MyoD and E-proteins. There is one potential alternate start site at Met280. Over aa101-287, there is less than 60% aa identity between human and mouse DEC-2. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-hDEC2, Anti-bHLHb3, Anti-BHLHB3, Anti-SHARP-1, Anti-bHLHe41, Anti-BHLHE41, Anti-Class B basic helix-loop-helix protein 3, Anti-Class E basic helix-loop-helix protein 41, Anti-Enhancer-of-split and hairy-related protein 1 |
Supplier: | United States Biological |
Supplier-Nr: | S1010-88B4 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Goat |
Species reactivity: | human |
Immunogen: | Recombinant corresponding to aa101-287 from human DEC2 expressed in E.coli. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03730 | Matching products |
UniProt ID : | Q9C0J9 | Matching products |
Gene ID | GeneID 79365 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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