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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG45472.50 | 50 µg | - | - |
6 - 14 business days* |
501.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated... more
Product information "Anti-SGT1 / ECD"
Protein function: Regulator of p53/TP53 stability and function. Inhibits MDM2- mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP (PubMed:16849563, PubMed:23880345). May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes (PubMed:19919181, PubMed:9928932). Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins (PubMed:19640839). The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex (PubMed:26711270). May play a role in regulation of pre-mRNA splicing (PubMed:24722212). {ECO:0000269, PubMed:16849563, ECO:0000269, PubMed:19640839, ECO:0000269, PubMed:19919181, ECO:0000269, PubMed:23880345, ECO:0000269, PubMed:26711270, ECO:0000305, PubMed:24722212, ECO:0000305, PubMed:9928932}. [The UniProt Consortium]
| Keywords: | Anti-ECD, Anti-hSGT1 {ECO:0000303|PubMed:9928932}, Anti-hSGT1 {ECO:0000303|PubMed:9928932}, Anti-Human suppressor of GCR two {ECO:0000303|PubMed:9928932}, Anti-Human suppressor of GCR two {ECO:0000303|PubMed:9928932}, Anti-Protein ecdysoneless homolog {EC |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG45472 |
Properties
| Application: | FC, ICC, IF, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant protein containing to human SGT1 / ECD |
| MW: | 73 kD |
| Format: | Affinity Purified |
Database Information
| UniProt ID : | O95905 | Matching products |
| Gene ID : | GeneID 11319 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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