Anti-SGOL2 (PACO03542)

Anti-SGOL2 (PACO03542)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-PACO03542.50 50 µg - -

9 - 20 business days*

320.00€
 
SGOL2 Antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC... more
Product information "Anti-SGOL2 (PACO03542)"
SGOL2 Antibody from Assay Genie with reactivity against Human and for use in ELISA, IHC applications. SGOL2 Antibody is Polyclonal and is a IgG isotype antibody from Assay Genie.. Protein function: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation. Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments. Involved in centromeric enrichment of AUKRB in prometaphase. [The UniProt Consortium]
Keywords: Anti-SGOL2, Anti-Tripin, Anti-Shugoshin-2, Anti-Shugoshin 2, Anti-Shugoshin-like 2
Supplier: Assay Genie
Supplier-Nr: PACO03542

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: synthesized peptide derived from the Internal region of human Sgo2.
Formula: affinity purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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