Anti-SGO2

Anti-SGO2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45271.50 50 µg - -

6 - 14 business days*

501.00€
 
Protein function: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated... more
Product information "Anti-SGO2"
Protein function: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation. Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments. Involved in centromeric enrichment of AUKRB in prometaphase. [The UniProt Consortium]
Keywords: Anti-SGOL2, Anti-Tripin, Anti-Tripin, Anti-Shugoshin 2, Anti-Shugoshin-2, Anti-Shugoshin 2, Anti-Shugoshin-2, Anti-Shugoshin-like 2, Anti-Shugoshin-like 2
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45271

Properties

Application: FC, ICC, IF, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein containing to human SGO2
MW: 145 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-SGO2"
Write a review
or to review a product.
Viewed