Anti-SF3B1

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA050275.25	25 µl		-		7 - 10 business days*		320.00€
ATA-HPA050275.100	100 µl		-		7 - 10 business days*		450.00€

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Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B... more

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Product information "Anti-SF3B1"

Protein function: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). Together with other U2 snRNP complex components may also play a role in the selective processing of microRNAs (miRNAs) from the long primary miRNA transcript, pri-miR-17-92. May also be involved in the assembly of the 'E' complex (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%

Keywords:	Anti-SF3B1, Anti-SAP155, Anti-SF3b155, Anti-SAP 155, Anti-Splicing factor 3B subunit 1, Anti-Spliceosome-associated protein 155, Anti-Pre-mRNA-splicing factor SF3b 155 kDa subunit
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA050275

Properties

Application:	WB, IHC, ICC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: LDSTGYYDQE IYGGSDSRFA GYVTSIAATE LEDDDDDYSS STSLLGQKKP GYHAPVALLN DIPQSTEQYD PFAEHRPPKI ADRED (ATA-APrEST85390)