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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA058111.25 | 25 µl | - |
7 - 10 business days* |
330.00€
|
|||
| ATA-HPA058111.100 | 100 µl | - |
7 - 10 business days* |
463.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone... more
Product information "Anti-SETD7"
Protein function: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys- 189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 97%
| Keywords: | Anti-SETD7, Anti-SET7/9, Anti-KIAA1717, Anti-H3-K4-HMTase SETD7, Anti-Lysine N-methyltransferase 7, Anti-SET domain-containing protein 7, Anti-Histone H3-K4 methyltransferase SETD7, Anti-Histone-lysine N-methyltransferase SETD7 |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA058111 |
Properties
| Application: | ICC, IHC, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: TLSLDEETVI DVPEPYNHVS KYCASLGHKA NHSFTPNCIY DMFVHPRFGP IKCIRTLRAV EADEELTVAY GYDHS (ATA-APrEST79780) |
Database Information
| KEGG ID : | K11431 | Matching products |
| UniProt ID : | Q8WTS6 | Matching products |
| Gene ID : | GeneID 80854 | Matching products |
| Protein Atlas Nr. : | ENSG00000145391 |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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