Anti-SETD4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ELK-ES19272.50	50 µl		-	-	10 - 14 business days*		173.00€
ELK-ES19272.100	100 µl		-	-	10 - 14 business days*		290.00€

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Protein function: Histone-lysine N-methyltransferase that acts as a regulator of cell... more

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Product information "Anti-SETD4"

Protein function: Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response (PubMed:31308046). Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively), leading to activate the transcription of pro- inflammatory cytokines IL6 and TNF-alpha. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3), thereby promoting heterochromatin formation (PubMed:31308046). Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs). [The UniProt Consortium] Recommended dilutions: WB 1:1000-2000. Cellular localization: Cytoplasm, cytosol . Nucleus .

Keywords:	Anti-SET domain-containing protein 4, SETD4 rabbit pAb
Supplier:	ELK Biotechnology
Supplier-Nr:	ES19272

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse
Immunogen:	Synthesized peptide derived from human SETD4 AA range: 193-243
Format:	Purified