Anti-SERPINB2

0.5mg/ml if reconstituted with 0.2ml sterile DI water. SERPINB2 is also known as PAI or PAI2. It is a coagulation factor that inactivates tPA and Urokinase. It is present in most cells, especially monocytes/macrophages. The protein exists in two forms, a 60-kDa extracellular glycosylated form and a 43-kDa intracellular form. It is present only at detectable quantities in blood during pregnancy, as it is produced by the placenta, and may explain partially the increased rate of thrombosisduring pregnancy. The majority of expressed SERPINB2 remains unsecreted due to the presence of an inefficient internal signal peptide. Protein function: Inhibits urokinase-type plasminogen activator. The monocyte derived PAI-2 is distinct from the endothelial cell- derived PAI-1. [The UniProt Consortium]