Anti-Septin 2

Anti-Septin 2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-210A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A304-210A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A304-210A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Filament-forming cytoskeletal GTPase. Required for normal organization of the... more
Product information "Anti-Septin 2"
Protein function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium by maintaining polyglutamylated microtubules, thus facilitating efficient vesicle transport, and by impeding MAP4 binding to tubulin. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation. Plays a role in ciliogenesis and collective cell movements. In cilia, required for the integrity of the diffusion barrier at the base of the primary cilium that prevents diffusion of transmembrane proteins between the cilia and plasma membranes: probably acts by regulating the assembly of the tectonic-like complex (also named B9 complex) by localizing TMEM231 protein. May play a role in the internalization of 2 intracellular microbial pathogens, Listeria monocytogenes and Shigella flexneri. [The UniProt Consortium]
Keywords: Anti-DIFF6, Anti-SEPT2, Anti-NEDD-5, Anti-Septin-2, Anti-Neural precursor cell expressed developmentally down-regulated protein 5
Supplier: Bethyl Laboratories
Supplier-Nr: A304-210A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Bovine, Orangutan)
Immunogen: synthetic peptide. The epitope recognized by A304-210A-T maps to a region between residue 275 to 325 of human Septin 2 using the numbering given in entry NP_001008491.1 (GeneID 4735).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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