Anti-SEPT7

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-14854.20 20 µl -

7 - 16 business days*

71.00€
E-AB-14854.60 60 µl -

7 - 16 business days*

143.00€
E-AB-14854.120 120 µl -

7 - 16 business days*

238.00€
E-AB-14854.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces... more
Product information "Anti-SEPT7"
This gene encodes a protein that is highly similar to the CDC10 protein of Saccharomyces cerevisiae. The protein also shares similarity with Diff 6 of Drosophila and with H5 of mouse. Each of these similar proteins, including the yeast CDC10, contains a GTP-binding motif. The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis. This human protein functions in gliomagenesis and in the suppression of glioma cell growth, and it is required for the association of centromere-associated protein E with the kinetochore. Alternative splicing results in multiple transcript variants. Several related pseudogenes have been identified on chromosomes 5, 7, 9, 10, 11, 14, 17 and 19 Protein function: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Required for normal progress through mitosis. Involved in cytokinesis. Required for normal association of CENPE with the kinetochore. Plays a role in ciliogenesis and collective cell movements. Forms a filamentous structure with SEPT12, SEPT6, SEPT2 and probably SEPT4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation (PubMed:25588830). [The UniProt Consortium]
Keywords: Anti-CDC10, Anti-SEPT7, Anti-Septin-7, Anti-CDC10 protein homolog, SEPT7 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-14854

Properties

Application: WB, IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human SEPT7
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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