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Promotion:
Save 30% on all primary antibodies by Arigo Biolaboratories!
*1
*1 Offer expires 16/12/2024
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Discount | Price |
---|---|---|---|---|---|---|---|---|
ARG55827.100 | 100 µl | - | - |
6 - 14 business days* |
30 %
|
584.00€
408.80€ |
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins.... more
Product information "Anti-SENP6 / SUSP1"
Protein function: Protease that deconjugates SUMO1, SUMO2 and SUMO3 from targeted proteins. Processes preferentially poly-SUMO2 and poly- SUMO3 chains, but does not efficiently process SUMO1, SUMO2 and SUMO3 precursors. Deconjugates SUMO1 from RXRA, leading to transcriptional activation. Involved in chromosome alignment and spindle assembly, by regulating the kinetochore CENPH-CENPI-CENPK complex. Desumoylates PML and CENPI, protecting them from degradation by the ubiquitin ligase RNF4, which targets polysumoylated proteins for proteasomal degradation. Desumoylates also RPA1, thus preventing recruitment of RAD51 to the DNA damage foci to initiate DNA repair through homologous recombination. [The UniProt Consortium]
Keywords: | Anti-SENP6, Anti-FKSG6, Anti-KIAA0797, EC=3.4.22.68, Anti-SUMO-1-specific protease 1, Anti-Sentrin-specific protease 6, Anti-Sentrin/SUMO-specific protease SENP6 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG55827 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human |
Immunogen: | KLH-conjugated synthetic peptide around aa. 1081-1112 of Human SENP6 / SUSP1 |
Format: | Purified |
Database Information
KEGG ID : | K08595 | Matching products |
UniProt ID : | Q9GZR1 | Matching products |
Gene ID | GeneID 26054 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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