Anti-SDHAF1

Anti-SDHAF1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ATA-HPA064277.25 25 µl -

7 - 10 business days*

335.00€
ATA-HPA064277.100 100 µl -

7 - 10 business days*

446.00€
 
Protein function: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an... more
Product information "Anti-SDHAF1"
Protein function: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954417, PubMed:19465911). Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants (PubMed:24954417). May act together with SDHAF3 (PubMed:24954417). Contributes to iron-sulfur cluster incorporation into SDHB by binding to SDHB and recruiting the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20 (PubMed:26749241). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 43% and to rat: 43%
Keywords: Anti-LYRM8, Anti-SDHAF1, Anti-SDH assembly factor 1, Anti-LYR motif-containing protein 8, Anti-Succinate dehydrogenase assembly factor 1, mitochondrial
Supplier: Atlas Antibodies
Supplier-Nr: HPA064277

Properties

Application: ICC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: GVGCQPDDGD SPRNPHDSTG A (ATA-APrEST92445)

Handling & Safety

Storage: -20°C
Shipping: +20°C (International: +20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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