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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ARG46461.50 | 50 µg | - | - |
10 - 15 business days* |
616.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an... more
Product information "Anti-SDHAF1"
Protein function: Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol (PubMed:24954417, PubMed:19465911). Promotes maturation of the iron-sulfur protein subunit SDHB of the SDH catalytic dimer, protecting it from the deleterious effects of oxidants (PubMed:24954417). May act together with SDHAF3 (PubMed:24954417). Contributes to iron-sulfur cluster incorporation into SDHB by binding to SDHB and recruiting the iron-sulfur transfer complex formed by HSC20, HSPA9 and ISCU through direct binding to HSC20 (PubMed:26749241). {ECO:0000269, PubMed:19465911, ECO:0000269, PubMed:24954417, ECO:0000269, PubMed:26749241}. [The UniProt Consortium]
| Keywords: | Anti-LYRM8, Anti-LYR motif-containing protein 8, Anti-LYR motif-containing protein 8, Anti-SDHAF1 {ECO:0000303|PubMed:19465911}, Anti-SDHAF1 {ECO:0000303|PubMed:19465911}, Anti-SDH assembly factor 1 {ECO:0000303|PubMed:19465911}, Anti-SDH assembly factor |
| Supplier: | Arigo Biolaboratories |
| Supplier-Nr: | ARG46461 |
Properties
| Application: | ICC, IF, WB |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human, mouse |
| Immunogen: | A 18 amino acid synthetic peptide within the last 50 amino acids of human SDHAF1 |
| MW: | 13 kD |
| Format: | Affinity Purified |
Database Information
| KEGG ID : | K18167 | Matching products |
| UniProt ID : | A6NFY7 | Matching products |
| Gene ID : | GeneID 644096 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +4°C (International: °C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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