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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ELK-ES10279.50 | 50 µl | - | - |
Request delivery time estimate |
169.00€
|
||
ELK-ES10279.100 | 100 µl | - | - |
Request delivery time estimate |
283.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Voltage-gated sodium channels are heteromeric proteins that function in the generation and... more
Product information "Anti-SCN1B"
Voltage-gated sodium channels are heteromeric proteins that function in the generation and propagation of action potentials in muscle and neuronal cells. They are composed of one alpha and two beta subunits, where the alpha subunit provides channel activity and the beta-1 subunit modulates the kinetics of channel inactivation. This gene encodes a sodium channel beta-1 subunit. Mutations in this gene result in generalized epilepsy with febrile seizures plus, Brugada syndrome 5, and defects in cardiac conduction. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2009], Protein function: Regulatory subunit of multiple voltage-gated sodium channel complexes that play important roles in excitable membranes in brain, heart and skeletal muscle. Enhances the presence of the pore-forming alpha subunit at the cell surface and modulates channel gating characteristics and the rate of channel inactivation. Modulates the activity of multiple pore-forming alpha subunits, such as SCN1A, SCN2A, SCN3A, SCN4A, SCN5A and SCN10A. [The UniProt Consortium] Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000. Cellular localization: [Isoform 1]: Cell membrane , Single-pass type I membrane protein . Perikaryon . Cell projection . Cell projection, axon . Detected at nodes of Ranvier on the sciatic nerve. ., [Isoform 2]: Perikaryon . Cell projection . Secreted . Detected on Purkinje cells and their cell projections and on neuronal cell projections. .
Keywords: | Anti-SCN1B, Anti-Sodium channel subunit beta-1, SCN1B rabbit pAb |
Supplier: | ELK Biotechnology |
Supplier-Nr: | ES10279 |
Properties
Application: | WB, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, rat, mouse |
Immunogen: | Synthesized peptide derived from part region of human protein |
MW: | 23 kD |
Format: | Purified |
Database Information
KEGG ID : | K04845 | Matching products |
UniProt ID : | Q07699 | Matching products |
Gene ID | GeneID 6324 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
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