Anti-SARS-CoV-2 (ORF8)

0.5mg/ml if reconstituted with 0.2ml sterile DI water. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped, positive-sense, single-stranded RNA virus that causes coronavirus disease 2019 (COVID-19). Virus particles include the RNA genetic material and structural proteins needed for invasion of host cells. Once inside the cell the infecting RNA is used to encode structural proteins that make up virus particles, nonstructural proteins that direct virus assembly, transcription, replication and host control and accessory proteins whose function has not been determined.~ ORF8 encodes a viral accessory protein. Protein function: Plays a role in modulating host immune response (PubMed:31986261). Binds to IL17RA receptor, leading to IL17 pathway activation and an increased secretion of pro-inflammatory factors. Contributes to cytokine storm during COVID-19 infection. [The UniProt Consortium]