Anti-SARS-CoV-2 ORF3A

Anti-SARS-CoV-2 ORF3A
Item number Size Datasheet Manual SDS Delivery time Quantity Price
G-CAB20234.20 20 µl -

9 - 20 business days*

103.00€
 
Protein function: Plays a role in viral egress via lysosomal trafficking (PubMed:33157038,... more
Product information "Anti-SARS-CoV-2 ORF3A"
Protein function: Plays a role in viral egress via lysosomal trafficking (PubMed:33157038, PubMed:33422265). Forms homotetrameric ion channels (viroporin) localized at endosomes and lysosomes, that may induce deacidification of lysosomes, allowing safe egress of virions via lysosomal trafficking (PubMed:33157038, PubMed:33422265,PubMed:34158638). Also blocks autolysosomes formation by binding and sequestering the host component VPS39 for homotypic fusion and protein sorting (HOPS) on late endosomes. This prevents fusion of autophagosomes with lysosomes, disrupting autophagy and facilitating virus egress (PubMed:33422265). [The UniProt Consortium]
Keywords: Anti-3a, Anti-ORF3a, Anti-Protein 3a, Anti-Protein X1, Anti-Protein U274, Anti-ORF3a protein, Anti-Accessory protein 3a
Supplier: Assay Genie
Supplier-Nr: CAB20234

Properties

Application: WB
Conjugate: No
Host: Rabbit
Species reactivity: SARS-CoV-2

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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