Anti-SAP97 / DLG1

Anti-SAP97 / DLG1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32206 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Disks large homolog 1 (DLG1), also known... more
Product information "Anti-SAP97 / DLG1"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Disks large homolog 1 (DLG1), also known as synapse-associated protein 97 or SAP97, is a protein that in humans is encoded by the SAP97 gene. SAP97 is expressed throughout the body in epithelial cells, including the kidney and brain. There is some evidence that SAP97 regulates cell-to-cell adhesion during cell death, and may interact with HPV. In the brain, SAP97's function is involved in the trafficking of transmembrane receptors from the ER to the plasma membrane. SAP97's function has been investigated by reducing its expression by knockout or increasing its expression heterologously. Mice in which the SAP97 gene has been knocked out die perinatally, have a cleft palate, and deficiencies in renal function. Overexpression of SAP97 in mammalian neurons leads to increased synaptic strength. Protein function: Essential multidomain scaffolding protein required for normal development. Recruits channels, receptors and signaling molecules to discrete plasma membrane domains in polarized cells. May play a role in adherens junction assembly, signal transduction, cell proliferation, synaptogenesis and lymphocyte activation. Regulates the excitability of cardiac myocytes by modulating the functional expression of Kv4 channels. Functional regulator of Kv1.5 channel. [The UniProt Consortium]
Keywords: Anti-hDlg, Anti-DLG1, Anti-SAP97, Anti-SAP-97, Anti-Disks large homolog 1, Anti-Synapse-associated protein 97, SAP97 Antibody / DLG1
Supplier-Nr: R32206

Properties

Application: WB, IHC (paraffin)
Antibody Type: Polyclonal
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Amino acids 1-165 of human SAP97 were used as the immunogen for the SAP97 antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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