Anti-SAMHD1

Anti-SAMHD1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-690A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-690A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-690A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Host restriction nuclease involved in defense response to virus. Has dNTPase... more
Product information "Anti-SAMHD1"
Protein function: Host restriction nuclease involved in defense response to virus. Has dNTPase activity and reduces cellular dNTP levels to levels too low for retroviral reverse transcription to occur. Blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May play a role in mediating proinflammatory responses to TNF-alpha signaling (PubMed:18546154, PubMed:19525956, PubMed:22056990, PubMed:24336198, PubMed:28229507). Has ribonuclease activity, acting on single-stranded RNA. This activity is essential for H1V-1 restriction (PubMed:25038827). [The UniProt Consortium]
Keywords: Anti-MOP5, Anti-DCIP, Anti-MOP-5, Anti-SAMHD1, Anti-dNTPase, EC=3.1.5.-, Anti-Monocyte protein 5, Anti-Dendritic cell-derived IFNG-induced protein, Anti-SAM domain and HD domain-containing protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A303-690A

Properties

Application: WB, IP, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Gorilla, Chimpanzee, Primates, Pygmy Chimpanzee)
Immunogen: synthetic peptide. The epitope recognized by A303-690A-T maps to a region between residue 450 and 500 of human SAM Domain and HD Domain 1 using the numbering given in entry NP_056289.2 (GeneID 25939).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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