Anti-SAA3

Enables Toll-like receptor 4 binding activity and chemoattractant activity. Acts upstream of or within several processes, including I-kappaB phosphorylation, cellular response to interleukin-1, and response to stilbenoid. Located in extracellular space. Is expressed in cerebellum, ileum, liver, reproductive system, and thymus. Orthologous to several human genes including SAA2 (serum amyloid A2). Protein function: Major acute phase reactant. Apolipoprotein of the HDL complex. In vitro exhibits antimicrobial activity against Escherichia coli, Streptococcus uberis and Pseudomonas aeruginosa. [The UniProt Consortium]