Anti-RUNX2

Anti-RUNX2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG67242.100 100 µl - -

10 - 15 business days*

616.00€
 
Protein function: Transcription factor involved in osteoblastic differentiation and skeletal... more
Product information "Anti-RUNX2"
Protein function: Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis (PubMed:28505335, PubMed:28738062, PubMed:28703881). Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2- mediated activation of the osteocalcin FGF-responsive element (OCFRE). Inhibits KAT6B-dependent transcriptional activation. {ECO:0000250, ECO:0000269, PubMed:11965546, ECO:0000269, PubMed:28505335, ECO:0000269, PubMed:28703881, ECO:0000269, PubMed:28738062}. [The UniProt Consortium]
Keywords: Anti-AML3, Anti-RUNX2, Anti-OSF-2, Anti-OSF-2, Anti-CBF-alpha-1, Anti-CBF-alpha-1, Anti-PEA2-alpha A, Anti-PEA2-alpha A, Anti-PEBP2-alpha A, Anti-PEBP2-alpha A, Anti-Oncogene AML-3, Anti-Oncogene AML-3, Anti-Acute myeloid leukemia 3 protein, Anti-Acute my
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG67242

Properties

Application: ICC, IF, IHC (paraffin), WB
Antibody Type: Monoclonal
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat
MW: 57 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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