Anti-RUNX1T1 / ETO

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG58296.50	50 µg		-	-	6 - 14 business days*		551.00€

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Protein function: Transcriptional corepressor which facilitates transcriptional repression via... more

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Product information "Anti-RUNX1T1 / ETO"

Protein function: Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes (PubMed:12559562, PubMed:15203199). Can repress the expression of MMP7 in a ZBTB33-dependent manner (PubMed:23251453). Can repress transactivation mediated by TCF12 (PubMed:16803958). Acts as a negative regulator of adipogenesis. The AML1-MTG8/ETO fusion protein frequently found in leukemic cells is involved in leukemogenesis and contributes to hematopoietic stem/progenitor cell self-renewal (PubMed:23812588). [The UniProt Consortium]

Keywords:	Anti-AML1T1, Anti-RUNX1T1, Anti-Protein ETO, Anti-Protein MTG8, Anti-Protein CBFA2T1, Anti-Eight twenty one protein, Anti-Cyclin-D-related protein, Anti-Zinc finger MYND domain-containing protein 2
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG58296

Properties

Application:	ELISA, IHC (paraffin), WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	E. coli-derived Human RUNX1T1/ETO recombinant protein (Position: T335-D510)