Anti-RSPO3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
NSJ-R35295-100UG	100 µg		-	-	3 - 10 business days*		836.00€

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0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s)... more

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Product information "Anti-RSPO3"

0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: R-spondin 3 Protein function: Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. [The UniProt Consortium]

Keywords:	Anti-RSPO3, Anti-PWTSR, Anti-hRspo3, Anti-hPWTSR, Anti-R-spondin-3, Anti-Roof plate-specific spondin-3, Anti-Protein with TSP type-1 repeat, Anti-Thrombospondin type-1 domain-containing protein 2, RSPO3 Antibody
Supplier:	NSJ Bioreagents
Supplier-Nr:	R35295

Properties

Application:	WB, ELISA (peptide)
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Goat
Species reactivity:	human
Immunogen:	Amino acids QHPSAKGNLCPPT were used as the immunogen for this RSPO3 antibody.
Format:	Purified