Anti-RPRD1B

Anti-RPRD1B
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-782A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-782A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-782A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of... more
Product information "Anti-RPRD1B"
Protein function: Interacts with phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit POLR2A, and participates in dephosphorylation of the CTD. Transcriptional regulator which enhances expression of CCND1. Promotes binding of RNA polymerase II to the CCDN1 promoter and to the termination region before the poly-A site but decreases its binding after the poly-A site. Prevents RNA polymerase II from reading through the 3' end termination site and may allow it to be recruited back to the promoter through promotion of the formation of a chromatin loop. Also enhances the transcription of a number of other cell cycle-related genes including CDK2, CDK4, CDK6 and cyclin-E but not CDKN1A, CDKN1B or cyclin-A. Promotes cell proliferation. [The UniProt Consortium]
Keywords: Anti-RPRD1B, Anti-C20orf77, Anti-Regulation of nuclear pre-mRNA domain-containing protein 1B, Anti-Cell cycle-related and expression-elevated protein in tumor
Supplier: Bethyl Laboratories
Supplier-Nr: A303-782A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Rat, Zebrafish, Chicken, Turkey, Bovine, Dog, Horse, Rabbit, Guinea Pig_10141, Pig, Panda, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, West Indian Ocean Coelacanth, Atlantic Salmon, Medaka Fish, Spotted Green Pufferfish)
Immunogen: synthetic peptide. The epitope recognized by A303-782A-T maps to a region between residue 276 and 326 of human Regulation of Nuclear Pre-mRNA Domain Containing 1B using the numbering given in entry NP_067038.1 (GeneID 58490).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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