Anti-RNF43

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG59435.50	50 µg		-	-	6 - 14 business days*		551.00€

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Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt... more

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Product information "Anti-RNF43"

Protein function: E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway (PubMed:18313049, PubMed:22575959, PubMed:22895187). Along with RSPO2 and ZNRF3, constitutes a master switch that governs limb specification. [The UniProt Consortium]

Keywords:	Anti-RNF43, EC=2.3.2.27, Anti-RING finger protein 43, Anti-E3 ubiquitin-protein ligase RNF43, Anti-RING-type E3 ubiquitin transferase RNF43
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG59435

Properties

Application:	WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	Recombinant protein corresponding to G24-Y197 of Human RNF43
MW:	85.7 kD
Format:	Antigen Affinity Purified