Item number Size Datasheet Manual SDS Delivery time Quantity Price
A304-111A-T 20 µl (2 blots) -

3 - 9 business days*

A304-111A-M 100 µl (10 blots) -

3 - 9 business days*

A304-111A 100 µl (100 µg) -

3 - 9 business days*

Protein function: Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific... more
Product information "Anti-RNF216"
Protein function: Isoform 1 acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down- regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Isoform 3 inhibits TNF and IL-1 mediated activation of NF-kappa-B. Promotes TNF and RIP mediated apoptosis. [The UniProt Consortium]
Keywords: Anti-TRIAD3, Anti-RNF216, EC=6.3.2.-, Anti-RING finger protein 216, Anti-Triad domain-containing protein 3, Anti-E3 ubiquitin-protein ligase RNF216, Anti-Zinc finger protein inhibiting NF-kappa-B, Anti-Ubiquitin-conjugating enzyme 7-interacting protein 1
Supplier: Bethyl Laboratories
Supplier-Nr: A304-111A


Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse (Expected: Orangutan, Rhesus Monkey, Chimpanzee, Northern White-cheeked Gibbon)
Immunogen: synthetic peptide. The epitope recognized by A304-111A-T maps to a region between residue 100 to 150 of human Ring Finger Protein 216 using the numbering given in entry NP_996999.1 (GeneID 54476).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Our products are for laboratory research use only: Not for administration to humans!
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