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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| ATA-HPA051773.25 | 25 µl | - |
7 - 10 business days* |
335.00€
|
|||
| ATA-HPA051773.100 | 100 µl | - |
7 - 10 business days* |
446.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates... more
Product information "Anti-RNF20"
Protein function: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 97% and to rat: 99%
| Keywords: | Anti-BRE1A, Anti-hBRE1, Anti-RNF20, Anti-BRE1-A, Anti-RING finger protein 20, Anti-E3 ubiquitin-protein ligase BRE1A, Anti-RING-type E3 ubiquitin transferase BRE1A |
| Supplier: | Atlas Antibodies |
| Supplier-Nr: | HPA051773 |
Properties
| Application: | ICC |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human |
| Immunogen: | Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IVNRYWSQFD ENIRIILKRY DLEQGLGDLL TERKALVVPE PEPDSDSNQE RKDDRERGEG QEPAFSFLAT LAS (ATA-APrEST91335) |
Database Information
| KEGG ID : | K10696 | Matching products |
| UniProt ID : | Q5VTR2 | Matching products |
| Gene ID | GeneID 56254 | Matching products |
Handling & Safety
| Storage: | -20°C |
| Shipping: | +20°C (International: +20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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