Anti-RIOK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ATA-HPA001620.25	25 µl		-		7 - 10 business days*		335.00€
ATA-HPA001620.100	100 µl		-		7 - 10 business days*		446.00€

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Protein function: Involved in regulation of type I interferon (IFN)-dependent immune response... more

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Product information "Anti-RIOK3"

Protein function: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843). [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 96% and to rat: 97%

Keywords:	Anti-SUDD, Anti-RIOK3, EC=2.7.11.1, Anti-sudD homolog, Anti-RIO kinase 3, Anti-Serine/threonine-protein kinase RIO3
Supplier:	Atlas Antibodies
Supplier-Nr:	HPA001620

Properties

Application:	IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human
Immunogen:	Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence: IGKGKDITTK HDEVVCGRKN TARMENFAPE FQVGDGIGMD LKLSNHVFNA LKQHAYSEER RSARLHEKKE HSTAEKAVDP KTRSLMYKMV NSGMLETITG CISTGKESVV FHAYGGSMED EKEDSKVIPT ECA (ATA-APrEST85149)