Anti-RIOK3

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ABS-KC-42083.50	50 µl		-	-	Request delivery time estimate		206.00€
ABS-KC-42083.100	100 µl		-	-	Request delivery time estimate		295.00€

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Protein function: Involved in regulation of type I interferon (IFN)-dependent immune response... more

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Product information "Anti-RIOK3"

Protein function: Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses. May act as an adapter protein essential for the recruitment of TBK1 to IRF3 (PubMed:24807708). Phosphorylates IFIH1 on 'Ser-828' interfering with IFIH1 filament assembly on long dsRNA and resulting in attenuated IFIH1-signaling (PubMed:25865883). Can inhibit CASP10 isoform 7-mediated activation of the NF-kappaB signaling pathway (PubMed:19557502). May play a role in the biogenesis of the 40S ribosomal subunit. Involved in the processing of 21S pre-rRNA to the mature 18S rRNA (PubMed:22418843). [The UniProt Consortium]

Keywords:	Anti-SUDD, Anti-RIOK3, EC=2.7.11.1, Anti-sudD homolog, Anti-RIO kinase 3, Anti-Serine/threonine-protein kinase RIO3
Supplier:	Absea
Supplier-Nr:	KC-42083

Properties

Application:	IHC
Antibody Type:	Monoclonal
Clone:	K40110_9B12
Conjugate:	No
Host:	Mouse
Species reactivity:	human
Immunogen:	recombinant human RIOK3
Format:	Solution

Database Information

KEGG ID :	K08872 \| Matching products
UniProt ID :	O14730 \| Matching products
Gene ID :	GeneID 8780 \| Matching products

Handling & Safety

Storage:	-20°C (avoid repeat freezing and thawing cycles)
Shipping:	+4°C (International: +4°C)

Caution
Our products are for laboratory research use only: Not for administration to humans!

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